UAS Labs Conducting UTI Study on Cran-Gyn DDS

EDEN PRAIRIE, Minn.Physicians at University of North Dakota School of Medicine and Mayo Clinic are conducting a clinical study using a proprietary formula, Cran-Gyn DDS, developed by Dr. S.K. Dash of UAS Laboratories Inc.

This new Womens Health Formula (Cran-Gyn DDS/UAS Probiotic Blend 005) containing a multi-species probiotic at 6 billion CFU/g, cranberry fruit extract and natural D-mannose, is the subject of a clinical study for women with a history of UTIs.  Physicians from UND School of medicine and Mayo Clinic have initiated this study to evaluate the potential for using alternative therapy to prevent recurrence of UTIs.  The study is expected to be completed later this year. 

The majority of lower UTIs are caused by a common fecal bacterium, E. coli.  E.coli adhesion to urinary tract epithelium is receptor-dependent. Studies using D-mannose demonstrated its ability to bind to approximately 80 percent of the E.coli (type 1-fimbrated) that cause problems, preventing them from attaching on to receptors in the urinary tract. Cranberry proanthocyanidins are able to bind to about 10 percent of the E.coli (P-fimbrated). Certain probiotic strains have demonstrated the ability to produce bacteriocins that can inhibit growth of E. coli in vitro. The combination of DDS Probiotics, natural D-mannose and cranberry fruit extract hold the promise of prevention of UTIs, maintenance of healthy intestinal flora, boosting the immune system and maintenance of healthy yeast levels. 

Approximately 50 percent of women report having a UTI at some point in their life. More than 30 percent suffer from recurrent problems. According to JAMA, UTIs result in nearly 11 million office visits and more than 350,000 hospitalizations per year in the United States. The most common treatment for UTIs is antibiotics.  ften the use of antibiotics to treat the problem results in bacterial resistance and secondary yeast infections. Many sufferers are interested in finding natural alternatives to the problem.