CORE Formulation Fights Metabolic Syndrome

FAIRFIELD, Calif.Cissus quadrangularis extract, taken as CORE (a formula from Soy Labs), helped in the fight against metabolic syndrome and obesity by significantly reducing weight and central obesity, as well as fasting blood glucose, total cholesterol and low-density lipoprotein (LDL) cholesterol, triglycerides and C-reactive protein (CRP) (Lipids in Health and Disease, 5:24, 2006). The randomized, double blind, placebo-controlled study involved 123 overweight and obese persons (47.2 percent male; 52.8 percent female; aged 19 to 50). The 92 obese (BMI >30) participants were randomized into three groups: placebo, formulation/no diet, and formulation/diet (restricted to 2,100 to 2,200 calories/d). The 31 overweight participants (BMI = 25 to 29) formed a fourth (no diet) treatment group. All participants received 541 mg twice daily of the CORE formula or placebo and remained on a normal or calorie-controlled diet. After eight weeks, statistically significant net reductions in weight and central obesity, as well as in fasting blood glucose, total cholesterol, LDL-cholesterol, triglycerides and CRP were observed in participants receiving the formulation, regardless of diet. Researchers concluded CORE appears to be useful in the management of weight loss and metabolic syndrome.

In the United States, more than 60 percent of adults are overweight or obese and 47 million suffer from metabolic syndrome, stated lead researcher, Julius Oben, Ph.D., University of Yaoundé, Cameroon. This study indicates that the Soy Labs CORE formula may provide significant help in the fight against both conditions.