Grape Seed Extract Maintains Healthy Blood Pressure

MILANA new study has shown Indenas Enovita®, a proprietary standardized grape seed extract rich in proanthocyanidins, has shown efficacy in maintaining healthy blood pressure compared to only diet and lifestyle modification.

The 4-month study involved 119 participants who were in good health with borderline hypertension, defined as pre-hypertension (120-139 mm Hg/80-89 mm Hg) and stage 1 hypertension (140-159 mm Hg/90-99 mm Hg). All participants modified diet (reduction in salt, alcohol and caffeinated drinks) and lifestyle (regular exercise, improvement of sleep time, relaxation and reduction of smoke). No other nutritional elements, vitamins or drugs were used in the observation period. No side effects were reported during the execution of the study.

Participants were divided into three groups depending on age and objective parameters evaluated, namely systolic and diastolic blood pressure, microcirculatory status (LDF), heart rate and plasma oxidative status. Group 1 (37 subjects) and group 2 (35 subjects) added Enovita to the management plan at two different daily dosages (300 mg/day for group 1; 150 mg/day for group 2), while subjects from group 3 (47 subjects) only implemented the management plan,  serving as the control. Results showed the blood pressure normalization was significantly higher in the Enovita supplementation groups starting from the 4th week of supplementation.

Taken together, our data suggest that GSPs, at least in the profile associated to Indenas Enovita, are worth considering to complement dietary and lifestyle changes associated to the maintenance of a healthy blood pressure status, with beneficial cardiovascular effect," said Dr. Gianni Belcaro, department of biomedical science, Gabriele DAnnunzio University Chieti-Pescara, and head of the study.

Among other benefits, grapeseed has been linked to the prevention of the development of Alzheimers disease.