UC-II® Study Reveals Joint Health Benefits

BENICIA, Calif.An abstract of Jay Udani's study on UC-II® was recently published in the Journal of Alternative and Complementary Medicine, further documenting the product's joint health benefits.

UC-IIs ability to improve joint function in healthy, exercising subjects was investigated in a randomized, double-blind, placebo-controlled study. Subjects included in the study had no prior history of arthritic disease or joint pain at rest, but they experienced joint discomfort with physical activity. Research showed benefits for knee extension, exercise duration and recovery.

By including healthy subjects in this study, and using non-disease endpoints as a measure of efficacy, it is believed that structure/function claims such as may help alleviate exercise-induced joint pain can be substantiated when manufacturers include 40 mg of UC-II to their finished product," said Jay Martin, vice president of sales and marketing for InterHealth.

Subjects were placed on a standardized stepmill procedure until they complained of knee discomfort. While on the stepmill, the "time to onset of discomfort" was measured, and it was also measured when subjects got off the stepmill. Subjects exercised longer before experiencing joint discomfort and recovered faster after exercising compared to baseline.

With increased FDA regulatory scrutiny over dietary supplement structure/function claims, it becomes more important to have healthy subject research to substantiate these types of claims," Martin said. "UC-II healthy subject research can help substantiate reduction in exercise-induced joint pain claims as well as provide strong substantiation for healthy joint flexibility, mobility and comfort claims."

A 2010 study also confirmed the safety profile of UC-II®.