Some Fruit Juices Lower Drug Absorption

PHILADELPHIA─ Common fruit juices, such as grapefruit, apple and orange, may lower the absorption of certain drugs, potentially wiping out their benefits, a new study revealed.

This research contradicts the 20 year-old findings that grapefruit juice can boost drug levels in the body, causing the potential for an overdose.

More recent findings suggest otherwise. A recent study, conducted by Dr. David G. Bailey, a professor of clinical pharmacology and his team, had a group of healthy individual take the high-blood-pressure drug fexofenadine in combination with an antihistamine. Study participants then consumed grapefruit juice, water containing naringin (the active ingredient in grapefruit juice) or water. Those who had consumed the grapefruit juice or the naringin, absorbed only half of the fexofenadine compared to those who took the drug with only water. These findings suggest that naringin blocks the full absorption of the drug. (Read more here)

Source: Flexnews