Longvida® Reduces Brain Aging Protein

NOBLESVILLE, Ind.Consuming Longvida® Optimized Curcumin (containing 80mg curcumin, from Verdure Sciences) significantly improved a number of health indicators, including plasma bet-amyloid a and a range of inflammatory and oxidative markers in a 30-day placebo-controlled randomized trial from the Ohio State University. This study, performed by Robert DiSilvestro, Ph.D., professor in the Department of Human Nutrition at the Ohio State University, Columbus, is slated for publication in an international peer-reviewed medical journal.

I think what was interesting about this study is that we saw a number of effects, not just one thing," DiSilvestro said. The kinds of effects we saw for the intervention could conceivably help people of different ages and health status."

According to researchers, beta-amyloid protein is thought to be involved with aging and possibly Alzheimers disease (AD). Epidemiological research shows amyloid-beta, a polypeptide that plays a significant part in healthy brain aging, begins accumulating during middle age.

The study found it was significantly lowered with Longvida, however the effect was not tremendously large. DiSilvestro said it was important because the dose was small (one capsule/d) and because the time period was so short.

To our knowledge, this is one of the first human trials on curcumin to show statistically significant effects on clinical endpoints in a healthy population," said Blake Ebersole, technical director of Verdure Sciences. The fact that such a low dose was needed to achieve effects in only 30 days is an interesting and unique finding as well, and adds to the substantial amount of pharmacokinetic and pharmacodynamic data compiled on Longvida."

These findings are discussed in Optimized Curcumin: Myth Versus Fact", a scientific white paper just released by Verdure Sciences.  The White Paper also discusses why all curcumin supplements are not created equal.

These findings are consistent with previous data from several major universities suggesting that beta-amyloid can be bound by curcumin and may be cleared from the brain," Ebersole said.  The clinical trial results are very exciting, and we anticipate more to follow."