MegaNatural BP® in New Metabolic Syndrome Study

DAVIS, Calif.Researchers at UC Davis are recruiting for the next obesity-related studies, in which one study will include Polyphenolics MegaNatural BP® grape seed extract. The new study comes on the heels of a previously published study in July 2009, indicating the use of MegaNatural BP grape seed extract, in conjunction with lifestyle modification, may effectively lower blood pressure in patients with metabolic syndrome.

The new double blind, placebo-controlled studies will also be conducted under the direction of C. Tissa Kappagoda, M.D. The first will measure the inflammatory markers in overweight subjects or subjects diagnosed with metabolic syndrome throughout a full days worth of high-fat meals. The second will look grape seed extracts (as MegaNatural BP) ability to suppress inflammatory markers. Inflammatory markers are associated with insulin resistance, a condition which can develop into type 2 diabetes.

If we can suppress the inflammatory response in a single meal with grape seed extract, then we might be able to give grape seed extract continually to suppress the impact on insulin resistance from frequent high-fat meals, explained Kappagoda. This could lead to an opportunity for a larger clinical trial to see if we can at least delay the onset of type 2 diabetes. It might allow us to buy time to institute other remedial measures with people diagnosed with metabolic syndrome.

We are excited MegaNatural BP is proving to be such an important product in the fight against the devastating effects of metabolic syndrome, said Anil Shrikhande, president of Polyphenolics.