SierraSil, Vincaria® Lower Cartilage Degradation,Inflammation

SierraSil, Vincaria® Lower Cartilage Degradation,Inflammation

CLEVELANDA breakthroughmechanism of action study found SierraSil, a mineral supplement, suppressescartilage degradation and inflammation when used alone or in conjunction withVincaria®, a cats claw extract. The findings, published in the Journalof the American Nutraceutical Association (JANA), werepresented at SupplySide West and at Natural Products Expo East.

The in vitro study, conducted at Case Western ReserveUniversity School of Medicine in Cleveland, used human cartilage tissue andcells obtained from patients at the time of knee surgery. Results show bothSierraSil and SierraSil with Vincaria significantly reduced the breakdown ofcartilage structural integrity caused by the pro-inflammatory cytokineInterleukin by 68 to 73 percent and 58 to 77 percent, respectively.

These results indicate that SierraSil and SierraSil withVincaria are likely to be effective anti-inflammatory agents in the treatment ofjoint pain and that these benefits are likely due to suppression of geneexpression, said Mark Miller, Ph.D., professor of cardiovascular sciences andpediatrics at Albany Medical College, N.Y.

SierraSil and SierraSil with Vincaria may offer excitingnew approaches to limiting the joint destruction and lack of mobility associatedwith arthritis.

SierraSil for this study was provided by Sierra MountainMinerals Inc. (www.sierrasil.com), a Vancouver-based nutraceutical company. Vincaria for this study was provided by RainforestNutritionals Inc. (www.rainforest-inc.com), a Phoenix-based nutraceutical andclinical research company.