The Untapped Potential of Isoflavones References

September 12, 2005

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September 12, 2005 Natural Products INSIDER
"Untapped Potential of Isoflavones" References

1. Zhang X et al. Soy food consumption is associated with lower risk ofcoronary heart disease in Chinese Women. J Nutr. 133, 9:2874-8, 2003. www.nutrition.org

2. 9. Jenkins DJ et al. Effects of high- and low-isoflavone soyfoods onblood lipids, oxidized LDL, homocysteine, and blood pressure in hyperlipidemicmen and women. Am J Clin Nutr. 76, 2:365-72. www.ajcn.org

3.Alexandersen P et al. Dietary phytoestrogens and estrogen inhibitexperimental atherosclerosis. Climacteric. 4, 2:151-9, 2001. www.parthpub.com/climacteric/home.html

4. Kris-Etherton PM and West SG. Soy protein with or without isoflavones:in search of a cardioprotective mechanism of action. Am J Clin Nutr. 81,1:5-6, 2005. www.ajcn.org/cgi/content/full/81/1/5

5. Prior RL and Cao G. Analysis of botanicals and dietary supplements forantioxidant capacity: a review. J Assoc Anal Chem Intl. 83:950-56,2000.

6. Yildiz MF et al. Effects of raloxifene, hormone therapy, and soyisoflavone on serum high-sensitive C-reactive protein in postmenopausal women.Int J Gynaecol Obstet. 90, 2:128-33, 2005. http://www.sciencedirect.com/science/journal/00207292

7. Nestel P et al. A biochanin-enriched isoflavone from red clover lowersLDL cholesterol in men. Eur J Clin Nutr. 58, 3:403-8, 2004. www.nature.com/ejcn

8. Campbell MJ et al. Effect of red clover-derived isoflavonesupplementation on insulin-like growth factor, lipid and antioxidant status inhealthy female volunteers: a pilot study. Eur J Clin Nutr. 58,1:173-9,2004. www.nature.com/ejcn

9. Vera R et al. Soy isoflavones improve endothelial function inspontaneously hypertensive rats in an estrogen-independent manner: role ofnitric-oxide synthase, superoxide, and cyclooxygenase metabolites. JPharmacol Exp Ther. 314, 3:1300-9, 2005. www.jpet.org

10. Oviedo PJ et al. EFffect of phytoestrogens genistein and daidzein onprostacyclin production by human endothelial cells. J Pharmacol Exp Ther.Epub ahead of print, Jul 26, 2005. www.jpet.org

11. Fuchs D et al. Genistein blocks homocysteine-induced alterations inthe proteome of human endothelial cells. Proteomics. 5, 11:2808-18,2005. http://www3.interscience.wiley.com/cgi-bin/jhome/76510741

12. Kumar NB et al. The specific role of isoflavones on estrogenmetabolism in premenopausal women. Cancer. 94, 4:1166-74, 2002. http://www3.interscience.wiley.com/cgi-bin/jhome/28741

13. Shao Z et al. Genistein exerts multiple suppressive effects on humanbreast carcinoma cells. Zhonghua Zhong Liu Za Zhi. 22, 5:362-5, 2000.

14. Lamartiniere CA et al. Daidzein: bioavailability, potential forreproductive toxicity, and breast cancer chemoprevention in female rats. ToxicolSci. 65, 2:228-38, 2002. http://toxsci.oupjournals.org

15. Goodman MT et al. Association of soy and fiber consumption with therisk of endometrial cancer. Am J Epidemiol. 146, 4:294-306, 1997.

16. Pfeiffer E et al. Isoflavones modulate the glucuronidation ofestradiol in human liver microsomes. Carcinogenesis. Epub ahead ofprint, Jul 28, 2005. http://carcin.oupjournals.org

17. Yan L and Spitznagel EL. Meta-analysis of soy food and risk ofprostate cancer in men. Int J Cancer. Epub ahead of print, Jun 8,2005. http://www3.interscience.wiley.com/cgi-bin/jhome/29331

18. Vij U et al. Phyto-oestrogens and prostatic growth. Natl MedJ India. 17, 1:22-6, 2004. www.aiims.ac.in/ragu/aiims/publ/nmji/nmji-main.htm

19. Kumar NB et al. The specific role of isoflavones in reducing prostatecancer risk. Prostate. 59, 2:141-7, 2004. http://www3.interscience.wiley.com/cgi-bin/jhome/34304

20. Hedlund TE et al. Long-term dietary habits affect soy isoflavonemetabolism and accumulation in prostatic fluid in caucasian men. J Nutr.135, 6:1400-6, 2005. www.nutrition.org

21. Kato K et al. Suppressive effects of dietary genistin and daidzin onrat prostate carcinogenesis. Japan J Cancer Res. 9, 8:786-91, 2000. www.jca.gr.jp

22. Hussain M et al. Soy isoflavones in the treatment of prostate cancer.Nutr Cancer. 47, 2:111-7, 2003.

23. Watkins BA et al. Protective actions of soy isoflavones and n-3 PUFAson bone mass in ovariectomized rats. J Nutr Biochem. 16, 8:479-88,2005. http://www.sciencedirect.com/science/journal/09552863

24. Atkinson C et al. The effects of phytoestrogen isoflavones on bonedensity in women: a double-blind, randomized, placebo-controlled trial. AmJ Clin Nutr. 79, 2:326-33, 2004. www.ajcn.org

25. Arjmandi BH and Smith BJ. Soy isoflavones' osteoprotective role inpostmenopausal women: mechanism of action. J Nutr Biochem. 13,3:130-137, 2002. http://www.sciencedirect.com/science/journal/09552863

26. Chen YM et al. Soy isoflavones have a favorable effect on bone loss inChinese postmenopausal women with lower bone mass: a double-blind, randomized,controlled trial. J Clin Endocrinol Metab. 88, 10:4740-7, 2003. http://jcem.endojournals.org

27. Upmalis DH et al. "Vasomotor symptom relief by soy isoflavoneextract tablets in postmenopausal women: a multicenter, double-blind,randomized, placebo-controlled study." Menopause. 7, 4:236-42, 2000.www.menopausejournal.com

28. Dornstauder E et al. Estrogenic activity of two standardized redclover extracts Menoflavon intended for large scale use in hormone replacementtherapy. J Steroid Biochem Mol Biol. 78, 1:67-75, 2001. www.sciencedirect.com/science/journal/09600760

29. Van de Weijer PH et al. Isoflavones from red clover Promensilsignificantly reduce menopausal hot flush symptoms compared with placebo. Maturitas.42, 3:187-93 2002. www.sciencedirect.com/science/journal/03785122

30. Bryant M et al. Effect of consumption of soy isoflavones onbehavioural, somatic and affective symptoms in women with premenstrual syndrome.Br J Nutr. 93, 5:731-9, 2005. http://www.ingentaconnect.com/content/cabi/bjn

31. Bu L and Lephart ED. Soy isoflavones modulate the expression of BADand neuron-specific beta III tubulin in male rat brain. Neurosci Lett.385, 2:153-7, 2005. http://www.sciencedirect.com/science/journal/03043940

32. Zhan S and Ho SC. Meta-analysis of the effects of soy proteincontaining isoflavones on the lipid profile. Am J Clin Nutr. 81,2:397-408, 2005. www.ajcn.org

33. Melzer J et al. [Complementary medicine: phytotherapy andsoyaisoflavones as phytoestrogens.] Zentralbl Gynakol. 126, 3:138-47,2004.

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