Orally disintegrating tablets

Orally disintegrating tablets (ODTs) are a popular delivery form found in many prescription, over-the-counter (OTC) medicines and dietary supplements. These technologies are often referred to as melt-in-mouth, rapimelt, rapid disintegrating, orodispersible, quick dissolving or porous tablets, not to be confused with chewable tablets that require chewing and swallowing. 

Because ODT’s dissolve in the mouth with saliva, they release the active drugs in pregastric, gastric and postgastric phases of the gastrointestinal (GI) system. On the contrary, conventional tablets must be swallowed with water for dissolution, released, and absorbed in the stomach and postgastric sites of the GI system.

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