Super CitriMax® Study Shows No Toxicity

BENICIA, Calif.—According to a recent study published in Toxicology Mechanisms and Methods, parental and offspring no-observed-adverse-effect level for a novel calcium/potassium salt of (-)-hydroxycitric acid (HCA-SX) was greater than 10,000 ppm in diet or equivalent to 1,018 and 1,524 mg/kg body weight/d in male and female rats, respectively (2008;18(5):433-42) (DOI:10.1080/15376510802084030). Sprague-Dawley rats (30/sex/group) were maintained on feed containing HCA-SX (as Super CitriMax®, from InterHealth), a natural plant extract from the dried fruit rind of Garcinia cambogia, at dose levels of 0, 1,000, 3,000, or 10,000 ppm for 10 weeks prior to mating, during mating, and for females, through gestation and lactation, across two generations. Dietary exposure of HCA-SX to parental male and female rats of both generations during the premating and mating periods, for both sexes, and during gestation and lactation in case of female rats, did not reveal any remarkable incidence of mortality or abnormal clinical signs. Compared to respective controls, HCA-SX exposure did not affect feed consumption or body weight at any of the exposure levels and it did not affect reproductive performance as evaluated by sexual maturity, fertility and mating, gestation, parturition, litter properties, lactation, and development of the offspring.
“This study is the latest in a massive body of research that confirms the broad spectrum safety of Super CitriMax,” said Paul Dijkstra, CEO, InterHealth Nutraceuticals Inc. “Super CitriMax has undergone more than two decades of safety and efficacy research at some of the nation’s most prestigious universities with more than 20 studies published in peer-reviewed journals. All research demonstrates that it is both efficacious and safe.”