Sustamine Raises L-Glutamine Levels

NEW YORKBlood levels of L-Glutaminethe most abundant amino acid in human muscles and bloodwere higher in healthy human participants after they ingested Sustamine, a GRAS (generally recognized as safe) dipeptide of liquid-stable L-Glutamine, according to a recent clinical study (Nutrition Research 2012 Apr 11).

L-glutamine is one of 20 amino acids found naturally in the human body, and is mainly generated in muscle tissue from glutamate and ammonia. It is prevalently used in the intestines and immune cells. Various clinical studies have shown it also can aid in muscle recovery after strenuous activity. A recent study showed Sustamine helped NCAA Division I basketball players increase their basketball performance, including shooting performance and visual acuity.

The study measured the L-glutamine blood levels of eight male participants after separately taking L-glutamine and Sustamine (L-Alanyl-L-Glutamine). Tests showed the L-glutamine level after Sustamine ingestion was 224-percent of that after L-glutamine ingestion. When allowance was made for the lower L-glutamine dose administered as height weight proportional (HWP), the peak plasma concentration and area under the plasma concentration curve were approximately the same as for Sustamine. The results suggested a greater transfer from the gut to plasma of L-glutamine when supplied as Sustamine and possibly also as HWP compared with to the same dose provided as the free amino acid.