Anitoxidant Defense References

March 28, 2005 - Natural Products Industry INSIDER
"Antioxidant Defense" References

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2. Krajcovicova-Kudlackova M, Dusinska M. "Oxidative DNA damage inrelation to nutrition." Neoplasma. 51, 5:30-3, 2004. www.neoplasma.sk

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4. Blomhoff R. "Dietary antioxidants and cardiovascular disease." CurrOpin Lipidol. 16, 1:47-54, 2005.

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6. de Champlain J et al. "Oxidative stress in hypertension." ClinExp Hypertens. 26, 7-8:593-601, 2004. www.dekker.com/servlet/product/productid/CEH

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11. Genkinger JM et al. "Fruit, vegetable and antioxidant intake andall-cause, cancer and cardiovascular disease mortality in a community-dwellingpopulation in Washington County, Maryland." Am J Epidemiol. 160,12:1223-33, 2004. www.aje.oupjournals.org

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15. Nagyova A et al. "Lipid peroxidation in men after dietarysupplementation with a mixture of antioxidant nutrients." Bratisl LekListy. 105, 7-8:277-80, 2004.

16. Konovalova GG et al. "Complex of vitamins and antioxidants protectslow-density lipoproteins in blood plasma from free radical oxidation andactivates antioxidant enzymes in erythrocytes from patients with coronary heartdisease." Bull Exp Biol Med. 136, 2:142-4, 2003.

17. Richer S et al. "Double-masked, placebo-controlled, randomized trialof lutein and antioxidant supplementation in the intervention of atrophicage-related macular degeneration: the Veterans LAST study (Lutein AntioxidantSupplementation Trial). Optometry. 75, 4:216-30, 2004.

18. Zandi PP et al. "Reduced risk of Alzheimer disease in users ofantioxidant vitamin supplements: the Cache County Study." Arch Neurol.61, 1:82-8, 2004. http://archneur.ama-assn.org

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20. Ramanathan K et al. "Ascorbic acid and alpha-tocopherol as potentmodulators of apoptosis on arsenic induced toxicity in rats." ToxicolLett. 156, 2:297-306, 2005. www.sciencedirect.com/science/journal/03784274

21. Simsek M, Naziroglu M, Erdinc A. "Moderate exercise with a dietaryvitamin C and E combination protects against streptozotocin-induced oxidativedamage to the kidney and lens in pregnant rats." Exp Clin EndocrinolDiabetes. 113, 1:53-9, 2005. www.thieme.de/fz/eced

22. Loong CC et al. "Antioxidant supplementation may improve renaltransplant function: a preliminary report." Transplant Proc. 36,8:2438-9, 2004.

23. Padayatty SJ et al. "Vitamin C as an antioxidant: evaluation of itsrole in disease prevention." J Am Coll Nutr. 22, 1:18-35, 2003. www.am-coll-nutr.org/jacn/jacn.htm

24. Kojo S. "Vitamin C: basic metabolism and its function as an index ofoxidative stress." Curr Med Chem. 11, 8:1041-64, 2004. www.bentham.org/cmc/

25. Konopacka M. "[Role of vitamin C in oxidative DNA damage.]" PostepyHig Med Dosw (Online). 58:343-8, 2004.

26. Moller P et al. "Vitamin C supplementation decreases oxidative DNAdamage in mononuclear blood cells of smokers." Eur J Nutr. 43,5:267-74, 2004. http://link.springer.de/link/service/journals/00394/

27. Attri J et al. "Effect of vitamin C supplementation on oxidative DNAdamage in an experimental model of lead-induced hypertension." Ann NutrMetab. 47, 6:294-301, 2003. www.karger.com/anm

28. Ward NC et al. "Effects of exposure to grape seed polyphenols andvitamin C on lipid peroxidation in vivo." Asia Pac J Clin Nutr. 13,Suppl:S76, 2004. www.healthyeatingclub.com/APJCN/ProcNutSoc/

29. Polidori MC et al. "Short-term and long-term vitamin Csupplementation in humans dose-dependently increases the resistance of plasma toex vivo lipid peroxidation." Arch Biochem Biophys. 423, 1:109-15,2004. www.sciencedirect.com/science/journal/00039861

30. Pfluger P et al. "Vitamin E: underestimated as an antioxidant."Redox Rep. 9, 5:249-54, 2004.

31. Naguib Y et al. "Antioxidant activities of natural vitamin Eformulations." J Nutr Sci Vitaminol (Tokyo). 29, 4:217-20, 2003. http://eishoku.bcasj.or.jp/journal-e.html

32. Fantappie O et al. "Vitamin E protects DNA from oxidative damage inhuman hepatocellular carcinoma cell lines." Free Radic Res. 38,7:751-9, 2004. www.tandf.co.uk/journals

33. Park OJ et al. "Effect of vitamin E supplementation on antioxidantdefense systems and humoral immune responses in young, middle-aged and elderlyKorean women." J Nutr Sci Vitaminol (Tokyo). 49, 2:94-9, 2003. http://eishoku.bcasj.or.jp/journal-e.html

34. Schaffer S, Muller WE, Eckert GP. "Tocotrienols: constitutionaleffects in aging and disease." J Nutr. 135, 2:151-4, 2005. www.nutrition.org

35. Yoshida Y, Niki E, Noguchi N. "Comparative study on the action oftocopherols and tocotrienols as antioxidant: chemical and physicaleffects." Chem Phys Lipids. 123, 1:63-75, 2003. www.sciencedirect.com/science/journal/00093084

36. Soelaiman IN, Ahmad NS, Khalid BA. "Palm oil tocotrienol mixture isbetter than alpha-tocopherol acetate in protecting bones against free-radicalinduced elevation of bone-resorbing cytokines." Asia Pac J Clin Nutr.13, Suppl:S11, 2004. www.healthyeatingclub.com/APJCN/ProcNutSoc/

37. Khanna S et al. "Molecular basis of vitamin E action: tocotrienolmodulates 12-lipoxygenase, a key mediator of glutamate-inducedneurodegeneration." J Biol Chem. 278, 44:43508-15, 2003. www.jbc.org

38. Theriault A, Chao JT, Gapor A. "Tocotrienol is the most effectivevitamin E for reducing endothelial expression of adhesion molecules and adhesionto monocytes." Atherosclerosis. 160, 1:21-30, 2002. www.elsevier.com/locate/atherosclerosis

39. Tiahou G et al. "Lack of oxidative stress in a selenium deficientarea in Ivory Coast--potential nutritional antioxidant role of crude palmoil." Eur J Nutr. 43, 6:367-74, 2004. http://link.springer.de/link/service/journals/00394/

40. Ogru E et al. "Vitamin E phosphate: an endogenous form of vitaminE." Presented at Free Radicals and Oxidative Stress, Ioannina, Greece, June26-29, 2003.

41. Munteanu A et al. "Modulation of cell proliferation and geneexpression by alpha-tocopheryl phosphates: relevance to atherosclerosis andinflammation." Biochem Biophys Res Comm. 318:311-6, 2004. www.sciencedirect.com/science/journal/0006291X

42. Rezk BM et al. "The extraordinary antioxidant activity of vitamin Ephosphate." Biochim Biophys Acta. 1683:16-21, 2004. www.elsevier.nl/locate/bba

43. Naziroglu M, Karaoglu A, Aksoy AO. "Selenium and high dose vitamin Eadministration protects cisplatin-induced oxidative damage to renal, liver andlens tissues in rats." Toxicology. 195, 2-3:221-30, 2004. www.elsevier.com/inca/publications/store/5/0/5/5/1/8

44. Noaman E et al. "Vitamin E and selenium administration as amodulator of antioxidant defense system: biochemical assessment andmodification." Biol Trace Elem Res. 86, 1:55-64, 2002. www.humanapress.com

45. Jacob C et al. "Sulfur and selenium: the role of oxidation state inprotein structure and function." Angew Chem Int Ed Engl. 42,39:4742-58, 2003.

46. Guzman DC et al. "Antioxidant effects of selenium in rat brain andthe stimulating role of nitric oxide." Nutr Neurosci. 6, 3:177-82,2003. www.tandf.co.uk/journals/titles/1028415x.html

47. Santamaria A et al. "Protective effects of the antioxidant seleniumon quinolinic acid-induced neurotoxicity in rats: in vitro and in vivostudies." J Neurochem. 86, 2:479-88, 2003. http://highwire.stanford.edu/jneurochem.shtml?uri=/

48. James AM, Smith RA, Murphy MP. "Antioxidant and prooxidantproperties of mitochondrial coenzyme Q." Arch Biochem Biophys. 423,1:47-56, 2004. www.sciencedirect.com/science/journal/00039861

49. Genova ML et al. "Mitochondrial production of oxygen radical speciesand the role of coenzyme Q as an antioxidant." Exp Biol Med (Maywood). 228,5:506-13, 2003.

50. Kamzalov S, Sohal RS. "Effect of age and caloric restriction oncoenzyme Q and alpha-tocopherol levels in the rat." Exp Gerontol.39, 8:1199-205, 2004.

51. Kwong LK et al. "Effects of coenzyme Q(10) administration on itstissue concentrations, mitochondrial oxidant generation, and oxidative stress inthe rat." Free Radic Biol Med. 33, 5:627-38, 2002. www.elsevier.com/locate/freeradbiomed

52. Mosca L et al. "Modulation of apoptosis and improved redoxmetabolism with the use of a new antioxidant formula." Biochem Pharmacol.63, 7:1305-14, 2002. www.sciencedirect.com/science/journal/00062952

53. Korkina L et al. "The protective and healing effects of a naturalantioxidant formulation based on ubiquinol and Aloe vera against dextransulfate-induced ulcerative colitis in rats." Biofactors. 18,1-4:255-64, 2003. www.iospress.nl/site/html/09516433.html

54. Lee CK et al. "The impact of alpha-lipoic acid, coenzyme Q10 andcaloric restriction on life span and gene expression patterns in mice." FreeRadic Biol Med. 36, 8:1043-57, 2004. www.elsevier.com/locate/freeradbiomed

55. Moini H, Packer L, Saris NE. "Antioxidant and prooxidant activitiesof alpha-lipoic acid and dihydrolipoic acid." Toxicol Appl Pharmacol.182, 1:84-90, 2002.

56. Smith AR et al. "Lipoic acid as a potential therapy for chronicdiseases associated with oxidative stress." Curr Med Chem. 11,9:1135-46, 2004. www.bentham.org/cmc/

57. Wollin SD, Jones PJ. "Alpha-lipoic acid and cardiovasculardisease." J Nutr. 133, 11:3327-30, 2003. www.nutrition.org

58. Nascimento NR et al. "Free radical scavengers improve the impairedendothelium-dependent responses in aorta and kidneys of diabetic rabbits." DiabetesRes Clin Pract. 61, 3:145-53, 2003. www.sciencedirect.com/science/journal/01688227

59. Garcia-Estrada J et al. "An alpha-lipoic acid-vitamin E mixturereduces post-embolism lipid peroxidation, cerebral infarction and neurologicaldeficit in rats." Neurosci Res. 47, 2:219-24, 2003.

60. Samuel S et al. "Protein oxidative damage in arsenic induced ratbrain: influence of DL-alpha-lipoic acid." Toxicol Lett. 155,1:27-34, 2005. www.sciencedirect.com/science/journal/03784274

61. Handelman GJ. "The evolving role of carotenoids in humanbiochemistry." Nutrition. 17, 10:818-22, 2001. www.journals.elsevierhealth.com/periodicals/nut

62. Ben-Dor A et al. "Carotenoids activate the antioxidant responseelement transcription system." Mol Cancer Ther. 4, 1:177-86, 2005. http://mct.aacrjournals.org/

63. Walrand S et al. "In vivo and in vitro evidences that carotenoidscould modulate the neutrophil respiratory burst during dietarymanipulation." Eur J Nutr. 44, 2:114-20, 2005. http://link.springer.de/link/service/journals/00394/

64. Chew BP, Park JS. "Carotenoid action on the immune response." JNutr. 134, 1:257S-61S, 2004. www.nutrition.org

65. Hak AE et al. "Prospective study of plasma carotenoids andtocopherols in relation to risk of ischemic stroke." Stroke. 35,7:1584-8, 2004. http://stroke.ahajournals.org/

66. Tamimi RM et al. "Plasma carotenoids, retinol and tocopherols andrisk of breast cancer." Am J Epidemiol. 161, 2:153-60. www.aje.oupjournals.org

67. Mannisto S et al. "Dietary carotenoids and risk of lung cancer in apooled analysis of seven cohort studies." Cancer Epidemiol BiomarkersPrev. 13, 1:40-8, 2004. http://cebp.aacrjournals.org/

68. Elmadfa I et al. "Effects of beta-carotene supplementation on freeradical mechanism in healthy adult subjects." Int J Vitam Nutr Res.74, 2:147-52, 2004.

69. Kleinjans JC et al. "In vitro investigations into the interaction ofbeta-carotene with DNA: evidence for the role of carbon-centered freeradicals." Carcinogenesis. 25, 7:1249-56, 2004. http://carcin.oupjournals.org

70. Rao AV. "Lycopene, tomatoes and the prevention of coronary heartdisease." Exp Biol Med (Maywood). 227, 10:908-13, 2002.

71. Fuhrman B et al. "Lycopene synergistically inhibits LDL oxidation incombination with vitamin E, glabridin, rosmarinic acid, carnosic acid orgarlic." Antioxid Redox Signal. 2, 3:491-506, 2000.

72. Tyssandier V et al. "Effect of tomato product consumption on theplasma status of antioxidant microconstituents and on the plasma totalantioxidant capacity in healthy subjects." J Am Coll Nutr. 23,2:148-56, 2004. www.am-coll-nutr.org/jacn/jacn.htm

73. Porrini M et al. "Daily intake of a formulated tomato drink affectscarotenoid plasma and lymphocyte concentrations and improves cellularantioxidant protection." Br J Nutr. 93, 1:93-9, 2005. www.cabi-publishing.org/journals/bjn

74. Riso P et al. "Lycopene and vitamin C concentrations increase inplasma and lymphocytes after tomato intake. Effects on cellular antioxidantprotection." Eur J Clin Nutr. 58, 10:1350-8, 2004. www.naturesj.com/ejcn

75. Guerin M, Huntley ME, Olaizola M. "Haematococcus astaxanthin:applications for human health and nutrition." Trends Biotechnol. 21,5:210-6, 2003.

76. Hussein G et al. "Antihypertensive and neuroprotective effects ofastaxanthin in experimental animals." Biol Pharm Bull. 28, 1:47-52,2005.

77. Iwamoto T et al. "Inhibition of low-density lipoprotein oxidation byastaxanthin." J Atheroscler Thromb. 7, 4:216-22, 2000. www.jstage.jst.go.jp/browse/jat

78. Ohgami K et al. "Effects of astaxanthin onlipopolysaccharide-induced inflammation in vitro and in vivo." InvestOphthalmol Vis Sci. 44:2694-2701, 2003.

79. Lee SJ et al. "Astaxanthin inhibits nitric oxide production andinflammatory gene expression by suppressing IkB kinase-dependent NF-kBactivation." Mol Cells. 16, 1:97-105, 2003.

80. Alves-Rodrigues A, Shao A. "The science behind lutein." ToxicolLett. 150, 1:57-83, 2004. www.sciencedirect.com/science/journal/03784274

81. Krinsky NI, Landrum JT, Bone RA. "Biologic mechanisms of theprotective role of lutein and zeaxanthin in the eye." Annu Rev Nutr.23:171-201, 2003. http://nutr.annualreviews.org/

82. Johnson MA, Macdonald TL. "Accelerated CuZn-SOD-mediated oxidationand reduction in the presence of hydrogen peroxide." Biochem Biophys ResCommun. 324, 1:446-50, 2004. http://www.sciencedirect.com/science/journal/0006291X

83. Muth CM et al. "Influence of an orally effective SOD on hyperbaricoxygen-related cell damage." Free Radic Res. 38, 9:927-32, 2004. www.tandf.co.uk/journals

84. Kong Y et al. "Influence of an orally effective superoxide dismutase(GliSODin)® on strenuous exercise-induced changes of blood antioxidant enzymesand plasma lactate." AACC Poster, presented July 2004.

85. Townsend DM et al. "The importance of glutathione in humandisease." Biomed Pharmacother. 57, 3-4:145-55, 2003. www.elsevier.nl/inca/publications/store/5/0/5/8/1/0

86. Todorova VK et al. "Oral glutamine (AES-14) supplementation inhibitsPI-3k/Akt signaling in experimental breast cancer." JPEN J ParenterEnteral Nutr. 27, 6:404-10, 2003.

87. Johnson AT et al. "Effect of glutamine on glutathione, IGF-I, andTGF-beta 1." J Surg Res. 111, 2:222-8, 2003. www.sciencedirect.com/science/journal/00224804

88. Keck AS, Finley JW. "Cruciferous vegetables: cancer protectivemechanisms of glucosinolate hydrolysis products and selenium." IntegrCancer Ther. 3, 1:5-12, 2004. http://ict.sagepub.com/

89. Herraiz T, Galisteo J. "Endogenous and dietary indoles: a class ofantioxidants and radical scavengers in the ABTS assay." Free Radic Res.38, 3:323-31, 2004. www.tandf.co.uk/journals

90. Gao X, Dinkova-Kostova AT, Talalay P. "Powerful and prolongedprotection of human retinal pigment epithelial cells, keratinocytes, and mouseleukemia cells against oxidative damage: the indirect antioxidant effects ofsulforaphane." PNAS. 98, 26:15221-6, 2001. www.pnas.org

91. Fahey JW, Zhang Y, Talalay P. "Broccoli sprouts: An exceptionallyrich source of inducers of enzymes that protect against chemicalcarcinogens." PNAS. 94:10367-72, 1997. www.pnas.org

92. Kurilich AC et al. "Antioxidant capacity of different broccoli(Brassica oleracea) genotypes using the oxygen radical absorbance capacity(ORAC) assay." J Agric Food Chem. 50, 18:5053-7, 2002. http://pubs.acs.org/journals/jafcau

93. Karasek M. "Melatonin, human aging and age-related diseases." ExpGerontol. 39, 11-12:1723-9, 2004.

94. Reiter RJ et al. "Pharmacological utility of melatonin in reducingoxidative cellular and molecular damage." Pol J Pharmacol. 56,2:159-70, 2004.

95. Leon J et al. "Melatonin and mitochondrial function." LifeSci. 75, 7:765-90, 2004.

96. Sofic E et al. "Antioxidant capacity of the neurohormonemelatonin." J Neural Transm. 112, 3:349-58, 2005.

97. Ozacmak VH et al. "Protective effect of melatonin on contractileactivity and oxidative injury induced by ischemia and reperfusion of ratileum." Life Sci. 76, 14:1575-88, 2005. www.sciencedirect.com/science/journal/00243205

98. Ahmed HH et al. "Cardioprotective activity of melatonin and itsnovel synthesized derivatives on doxorubicin-induced cardiotoxicity." BioorgMed Chem. 13, 5:1847-57, 2005.