MonaVie Active Shows Antioxidant Abilities

MonaVie Active™ is a juice blend containing fruits and berries with known antioxidant activity, including acai and a palm fruit, as the predominant ingredient. A recent study looked at the in vitro and in vivo antioxidant and anti-inflammatory properties of the juice blend (JB). (J. Agric. Food Chem. 2008;56 (18), 8326–33) (DOI:10.1021/jf8016157) The phytochemical antioxidants in the JB were primarily in the form of anthocyanins, predominantly cyanidin 3-rutoside, cyanidin 3-diglycoside and cyanidin 3-glucoside. The cell-based antioxidant protection of erythrocytes (CAP-e) assay showed antioxidants in the JB penetrated and protected cells from oxidative damage (P<0.001), whereas polymorphonuclear cells showed reduced formation of reactive oxygen species (P<0.003) and reduced migration toward three different pro-inflammatory chemoattractants. Then, a randomized, double blind, placebo-controlled, crossover trial with 12 healthy subjects examined the JB’s antioxidant activity in vivo. An increase in serum antioxidants at one hour (P<0.03) and two hours (P<0.015), as well as inhibition of lipid peroxidation at two hours (P<0.01) postconsumption was shown.