Svetol® Offers Slimming Success

NEW YORK—Extract of decaffeinated green coffee beans (as Svetol®, Berkem) was shown to reduce body mass index (BMI) and increase lean mass to fat mass ratio. The placebo-controlled, double blind clinical study (Phytothérapie, DOI:10.1007/s10298-006-0181- 7) was carried out by Dellalibera, Lemaire and Lafay; and enrolled a total of 50 participants, ages 19 to 75 with a body mass index (BMI) higher than 25. Thirty patients were administered a 200 mg capsule twice daily of Svetol, the rest received placebo.

“After 60 days of treatment, we observed in a significant manner a mean reduction in weight of 5.7 percent (an average reduction of 5 kg) and an increase in the lean to fat mass ratio of 4 percent—as compared to only 2.9 percent and 1.5 percent, respectively, in the placebo group,” said Sophie Lafay, Ph.D., scientific director at Berkem. Researchers concluded Svetol’s active molecules could decrease glucose intestinal absorption and inhibit glucose-6- phosphatase. “Thanks to the inhibition of G-6-Pase, the body has to get energy from another source, i.e. to burn fat from the adipose tissue,” Lafay said.

In collaboration with French National Agricultural Research Organization (INRA), Berkem studied the bioavailability of the main compound of Svetol, the 5-caffeoylquinic acid. The results obtained are in agreement with the suggested mechanism of action.

For more information, visit www.berkem.com or Booth #1629 at SupplySide East.